Its up to debate, but most information says general. But I would shoot it in the spots you want to lose the most. My buddy never said any about spot fat loss but he was also injecting IM in his arms and shoulders.
I couldn't tell you if ED injections would be enough because my buddy did just twice a day. I do know that he did get results with twice a day though. Not sure of the half life but that could be your answer if you can inject just once or if twice a day is needed.