Straight from the product description.
Seek advice from a health care practitioner prior to use if you have any pre-existing medical condition including (but not limited to): hypotension, hypertension, heart, liver, or thyroid disease, diabetes, psychiatric disease, asthma, pernicious anemia, anxiety, depression, seizure disorder, cardiac arrhythmias, stroke, difficulty urinating, due to prostate enlargement, or if you are taking an MAO inhibitor or any other prescription drug. Do not use if pregnant or nursing. Do not use this product if you are at risk of or treated for high blood pressure, heart, kidney, thyroid or psychiatric disease. Do not use if you are taking anti depressants. Not for use by women or anyone under the age of 21. If you are a professional or amateur athlete do not use this product as you could test positive for a urine or blood drug test. Do not use Spawn for more than 30 days.