^^ Ok cool.
Seems odd logic. It's just that empty stomach is nigh on impossible if you are meant to eat every 2-3hrs. A decent lump of meat may take 4hrs or more to digest.
In terms of speed of absorption I can see that empty stomach would be great. But in terms of bioavailability I don't see the issue. It being bound to anything is only going to be temporary (unless it binds to fibre, which is a possibility).