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Best Aromatase Inhibitor

P

pistoia

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Many body builders who take testosterone (and also men who are on testosterone replacement therapy (TRT) for medical reasons) need to be aware of the fact that testosterone converts to the female hormone estradiol through the aromatase enzyme. High levels of testosterone can cause high levels of estradiol, which in turn can cause the highly undesired development of female body characteristics, including gynecomastia.

To prevent these effects from taking place, there are two options:
  1. Estrogen blockers[/*:m:3t5jcmy2]
  2. Aromatase inhibitors[/*:m:3t5jcmy2]
Estrogen blockers, such as Tamoxifen (the generic name for Nolvadex), do not decrease the amount of estradiol flowing through the body. They simply attach themselves to the estrogen receptors in the body. The estrogen in the body will therefore be prevented from attaching itself to those receptors. However, while on some receptors Tamoxifen can act as an estrogen antagonist, in other cases it acts as an estrogen agonist. Some men who have taken Tamoxifen to prevent gynecomastia ended up developing other female-like characteristics, such as fat on their hips. Also, Tamoxifen is not a long-term solution because the estrogen is still flowing in the body. As soon as Tamoxifen is interrupted, that estrogen will still be there, free to cause damage.

The best solution is to take an aromatase inhibitor. For years, the most popular choice has been Anastrozole (the generic name for Arimidex). Recently, body builders and men on TRT have found another, more powerful aromatase inhibitor: Letrozole (the generic name for Femara). According to a recent scientific study, Letrozole is indeed much more powerful than Anastrozole:
[...] Letrozole suppresses tissue estrone (E1), estradiol (E2) and estrone sulfate (E1S) levels significantly below what has previously been recorded with anastrozole (89.0%, 83.4%, and 72.9% suppression, respectively). [...] Letrozole consistently suppressed each plasma estrogen fraction below the levels recorded for anastrozole: E2 (average suppression by 95.2% versus 92.8%; P = 0.018), E1 (98.8% suppression versus 96.3%; P = 0.003), and E1S (98.9% suppression versus 95.3%; P = 0.003).
Conclusion: Our data reveals that letrozole (2.5 mg o.d.) is more effective compared with anastrozole (1.0 mg o.d.) with respect to tissue as well as plasma estrogen suppression
 
G

GREGG VALENTINO

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MARCO IS AN EXPERT,,, LISTEN TO HIM, HE IS 100% CORRECT!!!!!!...FEMARA RULES,, NOTHING IS BETTER!!!
 
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