Top Quality Cialis @ PuritySourceLabs.ru

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EURO-PHARMACIES product

CIALIS 20 - 20mg/tab EP
Supplier:Euro-Pharmacies
Chemical Name:Tadalafil
Comes In:20mg tab
Dosage:15-30mg
Active time: aprox.20 hours
Classhosphodiesterase inhibitor

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Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence). Tadalafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors.
Tadalafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors.*
Erectile dysfunction is a condition where the penis does not harden and expand when a man is sexually excited, or when he cannot keep an erection.
tadalafil helps to maintain an erection after by increasing blood flow to the penis.
Tadalafil is also used to treat men who have symptoms of benign prostatic hyperplasia (BPH). BPH is caused by an enlarged prostate.
Tadalafil is also used to treat the symptoms of pulmonary arterial hypertension. This is high blood pressure that occurs in the main artery that carries blood from the right side of the heart (the ventricle) to the lungs.
Tadalafil works on the PDE5 enzyme in the lungs to relax the blood vessels. This will increase the supply of blood to the lungs and reduce the workload of the heart.

Tadalafil has the slowest absorption of the available PDE5 inhibitors with a mean of 2 hours to reach its maximum concentration, compared with about 50 minutes for sildenafil and vardenafil (Briganti et al 2005). The onset of action of tadalafil may occur in as early as 15 minutes of dosing, although successful erections occur in fewer than 40% of men at this time point .

Differences in gastrointestinal absorption with fatty meals explain the varying peak plasma concentration (Tmax) among the three PDE5 inhibitors.
Its most unique characteristic is its long half-life of 17.5 hours, which lends itself to a longer therapeutic window with on-demand dosing and effective steady-state plasma concentrations*.

Dosing/ absorption
Recommended starting doses of tadalafil are 10 mg for on-demand dosing and 2.5 mg for once-daily dosing, and these doses can then be titrated up or down according to the efficacy and tolerability (ICOS 2008). It is absorbed as a low-solubility and high-permeability, or Class 2, drug within the FDA Biopharmaceuticals Classification System (Gupta et al 2005). With oral ingestion, after first-pass metabolism, tadalafil is approximately 80% bioavailable, compared to 40% and 15% with sildenafil and vardenafil, respectively.

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IMHO Cialis is the best option for "mens health" issues.
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Tadalafil (Cialis)


History: Following on the coattails of Levitra, Cialis gained FDA approval in late 1993 and was subsequently produced by GlaxoSmithKline. It was the third big name ED drug released in a half a decade, eventually becoming the 2nd biggest seller in the ED marketplace


Method administration: Cialis is administered in oral form.


Drug Class: PDE5 Inhibitor.


Primary Use: In many respects, Cialis is amazingly similar to Viagra, although its active life is several times longer than that of its older brother, making it the more suitable candidate for long stretches of sexual activity or when sexual contact cannot be planned in advance. However, it is Cialis’s long active life which disqualifies it as a performance enhancer, as most athletic endeavors and weight training sessions are of a significantly shorter duration. For this reason, Viagra is the preferable alternative for performance enhancement, as it maintains an active life which coincides perfectly with most of these activities. Although all PDE5 Inhibitors work through the same basic pathway, personal response will vary from one person to the next, making personal experience invaluable in determining which drug works best for each individual.

********

Even if your high blood pressure (or hypertension) has caused erectile dysfunction (ED), you have every reason to be optimistic about the future and a healthy sex life. ED is a common problem associated with high blood pressure, but there are many proven treatments you can try.


A doctor's firstchoice for treating erection problems is usually one of the pills called PDE5 inhibitors. First there was Viagra. Now there's also Cialis, Levitra, and Staxyn. All of these drugs work in similar ways. They don't increase sexual desire. They make it physically possible to get an erection when you are aroused.


No one of them has been proven to work better than the others. But the time they take to start working and the duration of their effects vary. That's something you may want to consider based on your sexual habits. For example, does spontaneity matter to you, or do you usually plan sex ahead of time?


Viagra starts working in about 15 to 30 minutes and its effects last about two to four hours. Levitra starts working in about 30 to 60 minutes and lasts four to five hours. Cialis starts working in about 30 to 60 minutes and lasts as long as 36 hours.

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