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When it comes to rapid, undeniable muscle growth, Anadrol (Oxymetholone) sits at the top of the anabolic pyramid. Nicknamed the “A-bomb” for good reason, Anadrol delivers some of the most dramatic anabolic effects seen in the world of performance enhancement. Whether you’re a powerlifter chasing PRs or a bodybuilder entering a serious bulking phase, Anadrol adds sheer size and strength faster than virtually any other steroid.
But while its power is proven, so is the confusion surrounding how it works. This article will break down the science, correct the myths, and show you how to use Anadrol intelligently—including our three premium options from Sciroxx:
Anadrol is the oral form of Oxymetholone, first released by Syntex in 1959. While originally used in treating anemia and muscle-wasting disorders, it quickly became a staple in performance circles due to its potent mass-building effects.
Here’s the catch: although Anadrol is a DHT derivative, it doesn’t act like a typical DHT compound. It’s resistant to muscle deactivation via 3α-HSD enzymes, making it extremely active in muscle tissue. More interestingly, it has almost no affinity for the androgen receptor, meaning its effects are likely exerted through non-receptor mechanisms, including anti-catabolic pathways, possible glucocorticoid receptor interference, and direct stimulation of protein synthesis.
No steroid delivers faster weight gain than Anadrol. Users often report 6–12kg (13–26lbs) of weight gain in under 4 weeks, much of which is muscle mass.
Expect to add 20–40kg to key lifts rapidly. It’s highly favored among powerlifters and strongman competitors, especially in heavier weight classes.
Increases in red blood cells translate to better oxygen delivery, enhancing training endurance—especially during high-volume hypertrophy sessions.
Anadrol significantly improves recovery times, thanks to its potent anti-catabolic effects. It was once used to treat wasting diseases for exactly this reason.
Many assume Anadrol causes estrogenic side effects because of the noticeable water retention and bloating. But here’s the truth:
It’s believed that Anadrol may stimulate estrogen-like receptors directly or impact aldosterone pathways, which influence water and mineral retention. This pseudo-estrogenic effect explains the water gain—without actual increases in estrogen.
Pro tip: When used solo, Anadrol causes less fluid retention than when combined with aromatizing compounds like testosterone or Deca. Controlling sodium intake and diet composition can significantly reduce bloat.
Anadrol is often used at the start of a bulking cycle for quick gains, while waiting for long-acting injectables to kick in.
Example 4-Week Power Cycle:
Then transition to longer esters (Test E, Deca) and continue bulking.
Anadrol is not subtle—it’s a powerhouse. If you're looking for sheer size, explosive strength, and fast progress, Anadrol will deliver. But it’s also not a beginner’s toy, and it requires respectful, strategic use. Understanding its true mechanisms, managing side effects, and planning your stack intelligently makes all the difference.
And remember: most of what you’ve heard about Anadrol and estrogen is outdated or just plain wrong. Learn the science, control the variables, and use this tool for what it is: one of the most effective anabolic agents ever created.
But while its power is proven, so is the confusion surrounding how it works. This article will break down the science, correct the myths, and show you how to use Anadrol intelligently—including our three premium options from Sciroxx:
Anadrol 50 – Our flagship oral Oxymetholone product, offering fast U.S. domestic delivery, lab-tested purity, and serious muscle gains in just weeks.
Oxydex 50 – Designed for international customers, this version ensures global shipping with guaranteed delivery, making premium Oxymetholone accessible worldwide.
Anadrol Injection – A novel and unique version, favored by experienced users and professionals. The injectable route allows for optimal absorption, reduced liver strain (due to bypassing first-pass metabolism), and has been empirically linked to “dryer” gains with exceptional strength and power output. It’s ideal for those seeking maximum performance with lowered bloat and a slightly refined side effect profile.
What is Anadrol?
Anadrol is the oral form of Oxymetholone, first released by Syntex in 1959. While originally used in treating anemia and muscle-wasting disorders, it quickly became a staple in performance circles due to its potent mass-building effects.
- Anabolic rating: 320 (compare that to testosterone’s 100!)
- Androgenic rating: 45 (lower than expected, but side effects still possible and even pronounced in some individuals)
- Class: Dihydrotestosterone (DHT) derivative
Here’s the catch: although Anadrol is a DHT derivative, it doesn’t act like a typical DHT compound. It’s resistant to muscle deactivation via 3α-HSD enzymes, making it extremely active in muscle tissue. More interestingly, it has almost no affinity for the androgen receptor, meaning its effects are likely exerted through non-receptor mechanisms, including anti-catabolic pathways, possible glucocorticoid receptor interference, and direct stimulation of protein synthesis.
Why Athletes Love Anadrol
Ultimate Mass Builder
No steroid delivers faster weight gain than Anadrol. Users often report 6–12kg (13–26lbs) of weight gain in under 4 weeks, much of which is muscle mass.
Strength Surge
Expect to add 20–40kg to key lifts rapidly. It’s highly favored among powerlifters and strongman competitors, especially in heavier weight classes.
Red Blood Cell Boost
Increases in red blood cells translate to better oxygen delivery, enhancing training endurance—especially during high-volume hypertrophy sessions.
Faster Recovery
Anadrol significantly improves recovery times, thanks to its potent anti-catabolic effects. It was once used to treat wasting diseases for exactly this reason.
Busting the Estrogen Myth
Many assume Anadrol causes estrogenic side effects because of the noticeable water retention and bloating. But here’s the truth:
- Anadrol doesn’t aromatize (convert to estrogen). As a DHT derivative, it cannot undergo enzymatic conversion.
- It has very low progestogenic activity, unlike nandrolone (Deca), so that’s not the culprit either.
So why the bloat?
It’s believed that Anadrol may stimulate estrogen-like receptors directly or impact aldosterone pathways, which influence water and mineral retention. This pseudo-estrogenic effect explains the water gain—without actual increases in estrogen.

Dosage & Cycle Guidelines
User Level | Suggested Dosage |
---|---|
Beginner | Not ideal for first cycles. But if used, try a 25–75mg/day pyramid over 4 weeks. |
Intermediate | 50–100mg/day, ideally split into 2–3 doses. |
Advanced | Up to 200mg/day in 3–4 doses, but with a significantly higher risk of liver strain, BP issues, and appetite suppression. Use caution. |
Cycle Duration
- Typical cycle length: 4–5 weeks
- Do not taper—instead transition to a milder compound or move directly into PCT (Post Cycle Therapy).
- Liver protection (e.g., NAC, TUDCA) is essential.
Sample Blitz Cycle
Anadrol is often used at the start of a bulking cycle for quick gains, while waiting for long-acting injectables to kick in.
Example 4-Week Power Cycle:
- Testosterone Suspension – 100mg EOD (Every Other Day)
- Week 1: Anadrol 50mg/day (split AM/PM)
- Week 2–3: Anadrol 100mg/day (AM / pre-workout / PM)
- Week 4: Anadrol 150mg/day (50mg AM / 75mg pre-workout / 25mg PM)
Then transition to longer esters (Test E, Deca) and continue bulking.
Anadrol vs Other Popular Steroids
Steroid | Anadrol Comparison |
---|---|
Dianabol | Anadrol often causes faster, larger gains, but with more bloating. Dbol is gentler and better tolerated by most. |
Winstrol | Winstrol is a dry, cutting steroid. No water retention, opposite of Anadrol. Suitable for different goals. |
Testosterone | Testosterone aromatizes. Anadrol doesn’t. They work synergistically and are often stacked. |
Trenbolone | Tren offers dry gains with harsh side effects. Anadrol is wet, but easier on mood. Both are highly anabolic, and together can deliver freaky gains—but require experience. |
Final Thoughts
Anadrol is not subtle—it’s a powerhouse. If you're looking for sheer size, explosive strength, and fast progress, Anadrol will deliver. But it’s also not a beginner’s toy, and it requires respectful, strategic use. Understanding its true mechanisms, managing side effects, and planning your stack intelligently makes all the difference.
And remember: most of what you’ve heard about Anadrol and estrogen is outdated or just plain wrong. Learn the science, control the variables, and use this tool for what it is: one of the most effective anabolic agents ever created.