HCG & Testosterone: The Pregnyl Handbook for TRT, PCT, and Hormonal Optimization

[Sciroxx]

Proper cycle planning—and especially long-term TRT (Testosterone Replacement Therapy)—requires more than just the right anabolic/androgenic compound. It demands a smart approach to hormonal balance.


The testicular axis (also known as the HPG axis) is the foundation of male hormone function. Unfortunately, it’s severely suppressed during any testosterone or AAS (anabolic-androgenic steroid) use—and often doesn’t get the attention or support it deserves.


That’s where HCG (Human Chorionic Gonadotropin) enters the picture.


Originally developed for fertility treatment, HCG is now a well-recognized tool in performance enhancement and hormone optimization. It mimics LH (luteinizing hormone)—the hormone that tells your testes to produce testosterone naturally.

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Want the Full Breakdown?
We’ve summarized the key points for you here—but check out our mini-bible on the subject:
“Testosterone and HCG | HCG Testosterone Protocol | Cycle & TRT”

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Why Add HCG to Your Testosterone Regimen?​

Too many lifters and TRT users rely only on exogenous testosterone. It works—but it also shuts down your body’s own testosterone production. That’s where HCG plays a critical role.


What HCG Does:

• Stimulates the Leydig cells to produce testosterone—even during TRT or cycles
• Preserves testicular volume and function, preventing shrinkage
• Enhances libido, mood, and hormonal balance

Estrogen Control
Since HCG can raise estrogen levels, many users pair it with a low dose of Arimidex (0.25 mg twice per week) to avoid side effects like bloating and gynecomastia—without crashing estrogen entirely.

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Proven Protocols for Using HCG​

TRT Users:

• 250–500 IU of HCG, 2–3 times per week alongside testosterone
• Prevents long-term shutdown and helps maintain natural testosterone production
• Many cycle HCG (e.g., 3 weeks on / 3–4 weeks off) to avoid receptor desensitization

PCT After a Cycle:

• 1,000–2,000 IU every other day for 2–3 weeks
• Follow with Clomid or Nolvadex to kickstart the full HPTA recovery
• Faster rebound in natural testosterone and fertility

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Top Benefits of HCG-Testosterone Protocols​

• Maintains fertility and testicular size during TRT or cycles
• Boosts energy, mood, and sex drive by preserving internal hormone balance
• Prevents complete HPG axis shutdown during anabolic use
• Supports fat metabolism and lean body composition
• Ideal for men who want TRT without sacrificing natural function

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Example Stack (TRT or Cycle Support)​

• Testosterone Enanthate – 150–200 mg/week
• HCG – 500 IU, twice per week
• Arimidex – 0.25 mg, twice per week (adjust as needed)

This stack keeps testosterone levels optimized while preserving testicular health, preventing estrogen-related side effects, and supporting overall well-being.

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Where to Get Pharmaceutical-Grade HCG?​

For trusted, lab-tested HCG, check out:


[SciroxxOnline] – your go-to source for clinical-grade hormone support compounds.
Clinically backed. Athlete trusted. Expert supported.

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Final Thoughts​

HCG isn’t optional—it’s essential for anyone serious about long-term TRT, fertility preservation, or safe and effective recovery after a cycle. Whether you’re a beginner on TRT or a seasoned bodybuilder, this is one compound that earns its place in your protocol.