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As the 2025 bodybuilding season heats up, Terrence Ruffin is dominating headlines with back-to-back Classic Physique wins at the Pittsburgh Pro and New York Pro. Beyond his aesthetics and posing mastery lies a calculated and transparent performance-enhancing drug (PED) regimen. In this article, we dissect his complete cycle, timing, compounds, and insights, offering the most SEO-rich, evidence-backed analysis available.
Terrence Ruffin initiated his 2025 contest prep in January, following a 20-week protocol that evolves in intensity. His approach focuses on strategic compound rotation, controlled aromatase inhibitor management, and a moderate philosophy on orals and peptides.
Ruffin takes a layered approach to cutting fat—escalating from mild stimulants to potent beta-2 agonists:
Terrence's base compounds are testosterone, masteron, and primobolan, with trenbolone introduced 6–8 weeks before showtime.
Estrogen control plays a crucial role in Ruffin’s prep:
Ruffin incorporates Anavar (Oxandrolone) for strength retention and vascularity without excessive bloat:
Although Ruffin avoids most peptides, he occasionally turns to them for injury recovery.
He emphasizes mental health and moderation, citing adverse effects among younger bodybuilders misusing peptides.
Sample 20-Week PED Cycle Timeline based on the Gantt chart data, broken down by category and week:
These compounds form the anabolic foundation of the cycle:
Phased in gradually to maximize fat loss without overwhelming the system:
Introduced closer to the show for dryness, aggression, and definition:
To manage water retention and estrogenic side effects throughout the cycle:
Overview: Ruffin’s 2025 PED Cycle Strategy
Terrence Ruffin initiated his 2025 contest prep in January, following a 20-week protocol that evolves in intensity. His approach focuses on strategic compound rotation, controlled aromatase inhibitor management, and a moderate philosophy on orals and peptides.
Fat Loss Agents Used During Prep
Ruffin takes a layered approach to cutting fat—escalating from mild stimulants to potent beta-2 agonists:
Early Prep
- OTC Fat Burners – Non-specified thermogenics
- Yohimbine HCL – Dosage not specified
- Effect: Targeted fat loss; alpha-2 adrenergic receptor blocker
Advanced Stage
- Clenbuterol – Up to 100mcg daily
- Mechanism: Increases basal metabolic rate and lipolysis
- Risk: Not FDA-approved; serious cardiac risks
Anabolic Base Stack (Weeks 1–20)
Terrence's base compounds are testosterone, masteron, and primobolan, with trenbolone introduced 6–8 weeks before showtime.Compound | Dosage (est.) | Timeline | Purpose |
---|---|---|---|
Testosterone | N/A | Weeks 1–20 | Base anabolic |
Masteron | N/A | Weeks 1–20 | Hardness, estrogen control |
Primobolan | N/A | Weeks 1–20 | Lean gains, low water retention |
Trenbolone | N/A | Weeks 12–20 | Extreme conditioning, aggression |
Note: Ruffin didn’t disclose dosages, but competitive cycles often range 300–600mg/week per compound.
Estrogen Management
Estrogen control plays a crucial role in Ruffin’s prep:- Aromasin (Exemestane) – 25mg every 3 days
- Arimidex (Anastrozole) – 1mg every other day (during final weeks)
Oral Anabolics: Anavar
Ruffin incorporates Anavar (Oxandrolone) for strength retention and vascularity without excessive bloat:- Dosage: 50mg/day
- Duration: Weeks 14–19
- Note: Stopped 1 week before show for better look on stage
Peptides and Healing Agents
Although Ruffin avoids most peptides, he occasionally turns to them for injury recovery.Compound | Function | Current Usage |
---|---|---|
BPC-157 | Healing, recovery | Limited use |
TB-500 | Anti-inflammatory, tissue repair | Used occasionally |
GHRP-6 | Appetite stimulation | Previously used |
CJC-1295 | GH release, recovery, sleep aid | No current use |
Ruffin’s Warning to Young Athletes
Ruffin calls for mental stability before chemical enhancement. He warns that PEDs can damage developing brains and lead to long-term consequences socially, cognitively, and emotionally."Many kids are ruining relationships because of the side effects of this stuff." — Terrence Ruffin
Sample 20-Week PED Cycle Timeline (Hypothetical)

Base Gear (Weeks 1–20)
These compounds form the anabolic foundation of the cycle:- Testosterone: Full 20-week run (Jan 1 – mid-May)
- Masteron: Full 20-week run, supporting hardness and estrogen control
- Primobolan: Full 20-week run, promoting lean muscle with minimal water retention
Fat Burners & Cutting Agents
Phased in gradually to maximize fat loss without overwhelming the system:- OTC Fat Burners: Weeks 1–6 (Jan 1 – mid-Feb)
- Yohimbine HCL: Weeks 7–14 (Feb 12 – early April)
- Clenbuterol: Weeks 10–20 (Mar 10 – contest week)
Hardening Compounds
Introduced closer to the show for dryness, aggression, and definition:- Trenbolone: Weeks 12–18 (Mar 24 – early May)
- Anavar (50mg/day): Weeks 12–17 (Mar 24 – late April)
Estrogen Control
To manage water retention and estrogenic side effects throughout the cycle:- Aromasin (25mg every 3 days): Weeks 1–16 (Jan 1 – late April)
- Arimidex (1mg EOD): Weeks 17–20 (Apr 28 – contest peak)
Scientific Backing and Research Citations
- Yohimbine HCL: Demonstrated efficacy in fat loss among athletes (Ostojic, 2006)
- Clenbuterol: Increases fat oxidation, BMR, but poses serious health risks (Jessen et al., 2020)
- Testosterone: Proven to increase muscle protein synthesis (Griggs et al., 1989)
- BPC-157: Enhances GH receptor expression in fibroblasts (Chang et al., 2014)
- CJC-1295: Shown to support sleep, recovery, and body recomposition (Van Hout & Hearne, 2016)
Final Takeaways: Ruffin’s PED Philosophy
- Moderation over megadoses
- Precision in timing and dosing
- Caution toward orals and peptides
- Mental health > chemical shortcuts
- Education before experimentation