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EPO Micro-Dosing May Be Detected by New Test
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The new anti-doping test could detect EPO micro-dosing after 48 hours according to French scientists.
Athletes have never stopped injecting recombinant erythropoietin (rEPO) to enhance their performance in spite of efforts by anti-doping agencies to deter its use. The use of EPO remains widespread in large part because athletes can get away with it.
The athletes have stayed a step ahead of the anti-dopers in the never-ending cat-and-mouse game. The EPO doping strategy of “micro-dosing” has mostly allowed athletes to avoid detection. But the anti-dopers believe they are close to putting an end to this pracctice.
The breakthrough in EPO detection will force athletes to stop using EPO — or adapt.
Michael Audran, the director of the Laboratory of the Agence Française de lutte contre le Dopage (AFDL) in Châtenay-Malabry, announced the breakthrough at a recent AFDL meeting this summer.
The new EPO test has reportedly increased the detection window from a maximum of 24 hours to over 48 hours. For example, a 60-kilogram rider who injected 600 IU would fail a drug tested performed on blood sample collected 48 hours following the micro-dodsing injection.
Athletes have eluded previous attempts, such as the Athlete Biological Passport (ABP), to detect doping by using a combination of blood transfusions and micro-dosing of rEPO. Cyclists, for example, has undergone blood transfusions for a short period of two weeks and have maintained the benefits with micro-doses of EPO every 48 hours.
“It is important [for cheating athletes] to spend 24 to 48 hours [avoiding] detection, because in these protocols, it is estimated that cheaters make microdoses every two days,” Audran explained. “We can detect microdoses EPO a minimum of 48 hours after taking, while it is now difficult to arrive at 24 hours.”
The longer detection-window effectively thwarts the strategy of micro-dosing EPO every 48 hours.
The new EPO test has yet to be fully validated by the World Anti-Doping Agency (WADA). But the Châtenay-Malabry laboratory is confident that it will meet WADA’s approval. The researchers expect the new EPO test to be implement as early as 2020.
Athletes have never stopped injecting recombinant erythropoietin (rEPO) to enhance their performance in spite of efforts by anti-doping agencies to deter its use. The use of EPO remains widespread in large part because athletes can get away with it.
The athletes have stayed a step ahead of the anti-dopers in the never-ending cat-and-mouse game. The EPO doping strategy of “micro-dosing” has mostly allowed athletes to avoid detection. But the anti-dopers believe they are close to putting an end to this pracctice.
The breakthrough in EPO detection will force athletes to stop using EPO — or adapt.
Michael Audran, the director of the Laboratory of the Agence Française de lutte contre le Dopage (AFDL) in Châtenay-Malabry, announced the breakthrough at a recent AFDL meeting this summer.
The new EPO test has reportedly increased the detection window from a maximum of 24 hours to over 48 hours. For example, a 60-kilogram rider who injected 600 IU would fail a drug tested performed on blood sample collected 48 hours following the micro-dodsing injection.
Athletes have eluded previous attempts, such as the Athlete Biological Passport (ABP), to detect doping by using a combination of blood transfusions and micro-dosing of rEPO. Cyclists, for example, has undergone blood transfusions for a short period of two weeks and have maintained the benefits with micro-doses of EPO every 48 hours.
“It is important [for cheating athletes] to spend 24 to 48 hours [avoiding] detection, because in these protocols, it is estimated that cheaters make microdoses every two days,” Audran explained. “We can detect microdoses EPO a minimum of 48 hours after taking, while it is now difficult to arrive at 24 hours.”
The longer detection-window effectively thwarts the strategy of micro-dosing EPO every 48 hours.
The new EPO test has yet to be fully validated by the World Anti-Doping Agency (WADA). But the Châtenay-Malabry laboratory is confident that it will meet WADA’s approval. The researchers expect the new EPO test to be implement as early as 2020.
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