GLP-1s, New Compounds, and Superdrol Toxicity

[rxmuscle]

Dave tackled some hot topics on the latest Ask Dave episode. One of the biggest questions was about GLP-1 agonists like semaglutide, tirzepatide, and others being used during prep. His advice: stop them two weeks before a show. They slow digestion, which hurts carb loading. By pulling them early, gastric motility returns to normal, allowing better glycogen storage and less stomach distress.

He also broke down his power-building program, explaining it’s best used in the offseason for 6–8 weeks when food and recovery are high. Heavy compound lifts like squats, bench, and deadlifts build the base strength that carries over into other movements.

Supplement deals were mentioned too—Titan Medical is running \$50 off growth peptides like CJC-1295, MK-677, IGF-1 LR3, and more.



Other Q\&A highlights:

• Old vs. new school competition: Today’s athletes compete less often, partly due to higher costs and social media income opportunities.
• EQ cypionate rumors: In theory, it could exist as a different ester, but Dave hasn’t seen it. If legit, it works the same as regular EQ.
• Expired gear: Most oils remain stable for years if stored properly. Potency loss is minimal.
• Carb rotation diets: Dave likes inserting high-fat/no-carb days to keep metabolism responsive and muscles full.
• Fertility on TRT: For best results, come off HRT completely and follow a full fertility protocol with HCG, HMG, and Clomid.
• Superdrol: Extremely toxic—he doesn’t recommend it. Stick to injectables for safer gains.
• Amino acids before cardio: Bad idea—your body will convert them to glucose, blunting fat loss.
• Winstrol timing: Best used at 25–50 mg daily in the final 6–8 weeks of prep.
• Test injections: Intramuscular is always better than subQ.
• Cramping fixes: Try Gatorade or coconut water for electrolytes, or tonic water with quinine for clenbuterol cramps.
• Nick Walker’s training: He embodies “stimulate, don’t annihilate”—short, intense, heavy work with results to prove it.
• Natural fat-loss plateaus: Cheat meals, cardio variation, and smart diet tweaks help keep things moving.

Dave wrapped up from Pittsburgh, where he’s covering the North American Championships, one of the biggest amateur weekends of the year, and teased more content including his “pharmacy” video from India.