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Dave Palumbo and RX Muscle take viewer questions in a packed Ask Dave episode that covers everything from the current anabolic steroid supply to longevity supplements and the most freakish physiques Dave has ever seen in person.
The steroid shortage and what it means for bodybuilding Dave starts with the hot topic. People are worried there is a shortage of anabolic steroids because of raw material restrictions from China. He explains that stricter regulations and tariffs are slowing down the flow of raws, but he actually sees a positive side.
He never fully trusted many Chinese raws anyway. In his view, a lot of the underground products are underdosed, dirty, or not what they claim. That is one reason modern bodybuilders push such high doses. The gear is weaker than what was on the market 10 to 15 years ago.
Dave thinks the demand will always be filled. Raws may shift to other countries like India or even be produced more in the United States. He also expects growth from legitimate hormone and rejuvenation clinics that prescribe real pharmaceuticals. That would mean cleaner products, more predictable dosing, and less guessing for competitors.
Estradiol testing and why men should use the ultrasensitive test A viewer asks about estradiol bloodwork ranges. Dave explains that standard estradiol tests work well for women but often read falsely high for men.
He prefers the ultrasensitive estradiol test for male athletes. Many guys panic when a normal test flags “high estrogen,” but the ultrasensitive test often shows they are actually in range. His rule: if you are a man and you can order the ultrasensitive test, do it. Women can use either method.
Healing peptides instead of growth hormone Titan Medical Center sponsors a segment where Dave talks about BPC, TB500, and KPV now combined in one injectable. He loves this for injury repair and chronic pain.
Since his thyroid cancer and surgery, Dave refuses to use growth hormone because of cancer risk. He says these peptides often work better for healing than GH ever did for him. They will not build muscle like GH, but for recovery, he feels they are superior.
Essential fats, stubborn fat, and why everyone should use an EFA supplement On supplements, Dave keeps the base simple. Whether you are natural, enhanced, male, or female, he says three things never change:
• You need essential fatty acids • You need vitamins, minerals, antioxidants, and polyphenols • You need fiber
He uses his own Species Nutrition line as examples. Omegalyze covers omega-3 and omega-6 essential fats. Mineralize covers the micronutrients. Fiberlyze or similar high-quality psyllium fiber supports digestion, bowel movements, and gut health.
He also talks about his macadamia nut oil. It is not essential, but it is a great monounsaturated fat for heart health, fat loss, and cooking. He explains that a lack of essential fats can make the body “hoard” fat, especially in the butt and thighs for women and the lower back and waist for men. Once people start taking the right amount of essential fatty acids, those stubborn areas often begin to lean out.
Top supplements and health support for enhanced lifters For lifters on gear, Dave adds a few more key items:
• Liver support such as TUDCA or milk thistle based products, especially with orals • Blood pressure control with an ACE inhibitor or ARB if needed, to protect the kidneys • Plenty of fiber, especially if you are on GLP-1 drugs that slow digestion and cause constipation
For longevity he likes NAD+ (from Titan Medical Center), injectable glutathione, and a sensible melatonin dose at night. He is skeptical of metformin for bodybuilders due to lower IGF-1, and he wants no part of rapamycin or hype around telomere-length supplements.
The freakiest bodybuilder Dave ever saw The video title teaser pays off when a viewer asks: who was the freakiest bodybuilder Dave ever saw in person?
For men, he does not hesitate. Greg Kovacs. At 6'2"–6'2.5" and around 420 pounds, Greg made even a 320-pound Dave Palumbo look small. Walking side by side, people ignored Dave and stared at Kovacs. The structure was not perfect, but in terms of pure mass and shock factor, no one came close.
For women, he points to Iris Kyle. He believes at her best she had the greatest female physique of all time, comparing her impact to Ronnie Coleman. In clothes she did not look huge, but onstage she was unreal.
PCT, TRT and age Another viewer asks if PCT is needed after 60 or if you should just go straight to TRT. Dave says it depends on your goals.
If you still compete and run full cycles, he wants you to do a full cleanout: • Two weeks HCG • Two weeks Clomid • Then four weeks completely off
That break lets androgen receptors upregulate so you respond better to the next cycle or even standard TRT. If you are done competing and only want to feel good on lifelong replacement, you can go directly to TRT and stay there.
Statins, heart scans, and dementia risk On statins, Dave is firm. If your cardiac CT scan with contrast shows a very low score and clean arteries, he would not touch statins even with high LDL. Cholesterol is needed to repair myelin sheaths for nerve function, so drugs that crush cholesterol worry him for brain health. He notes links between long-term statin use and early dementia.
He would only consider statins in a serious high-risk case: strong family history, high cholesterol, and proven plaque in the arteries.
News, RX content and why this episode is worth watching Near the end, they update viewers on RX Muscle shows. They talk about an emotional After Hours episode with Amin Ali before he reports to prison, clarify the toxicology report on the death of Haley McNabb, and plug Heavy Muscle Radio where they break down Andrew Jacked’s big win at the Romania Pro and what it could mean for the 2026 Olympia lineup.
If you care about bodybuilding health, gear, smart supplement use, and freaky mass legends like Greg Kovacs and Iris Kyle, this Ask Dave episode is a strong watch.
The steroid shortage and what it means for bodybuilding Dave starts with the hot topic. People are worried there is a shortage of anabolic steroids because of raw material restrictions from China. He explains that stricter regulations and tariffs are slowing down the flow of raws, but he actually sees a positive side.
He never fully trusted many Chinese raws anyway. In his view, a lot of the underground products are underdosed, dirty, or not what they claim. That is one reason modern bodybuilders push such high doses. The gear is weaker than what was on the market 10 to 15 years ago.
Dave thinks the demand will always be filled. Raws may shift to other countries like India or even be produced more in the United States. He also expects growth from legitimate hormone and rejuvenation clinics that prescribe real pharmaceuticals. That would mean cleaner products, more predictable dosing, and less guessing for competitors.
Estradiol testing and why men should use the ultrasensitive test A viewer asks about estradiol bloodwork ranges. Dave explains that standard estradiol tests work well for women but often read falsely high for men.
He prefers the ultrasensitive estradiol test for male athletes. Many guys panic when a normal test flags “high estrogen,” but the ultrasensitive test often shows they are actually in range. His rule: if you are a man and you can order the ultrasensitive test, do it. Women can use either method.
Healing peptides instead of growth hormone Titan Medical Center sponsors a segment where Dave talks about BPC, TB500, and KPV now combined in one injectable. He loves this for injury repair and chronic pain.
Since his thyroid cancer and surgery, Dave refuses to use growth hormone because of cancer risk. He says these peptides often work better for healing than GH ever did for him. They will not build muscle like GH, but for recovery, he feels they are superior.
Essential fats, stubborn fat, and why everyone should use an EFA supplement On supplements, Dave keeps the base simple. Whether you are natural, enhanced, male, or female, he says three things never change:
• You need essential fatty acids • You need vitamins, minerals, antioxidants, and polyphenols • You need fiber
He uses his own Species Nutrition line as examples. Omegalyze covers omega-3 and omega-6 essential fats. Mineralize covers the micronutrients. Fiberlyze or similar high-quality psyllium fiber supports digestion, bowel movements, and gut health.
He also talks about his macadamia nut oil. It is not essential, but it is a great monounsaturated fat for heart health, fat loss, and cooking. He explains that a lack of essential fats can make the body “hoard” fat, especially in the butt and thighs for women and the lower back and waist for men. Once people start taking the right amount of essential fatty acids, those stubborn areas often begin to lean out.
Top supplements and health support for enhanced lifters For lifters on gear, Dave adds a few more key items:
• Liver support such as TUDCA or milk thistle based products, especially with orals • Blood pressure control with an ACE inhibitor or ARB if needed, to protect the kidneys • Plenty of fiber, especially if you are on GLP-1 drugs that slow digestion and cause constipation
For longevity he likes NAD+ (from Titan Medical Center), injectable glutathione, and a sensible melatonin dose at night. He is skeptical of metformin for bodybuilders due to lower IGF-1, and he wants no part of rapamycin or hype around telomere-length supplements.
The freakiest bodybuilder Dave ever saw The video title teaser pays off when a viewer asks: who was the freakiest bodybuilder Dave ever saw in person?
For men, he does not hesitate. Greg Kovacs. At 6'2"–6'2.5" and around 420 pounds, Greg made even a 320-pound Dave Palumbo look small. Walking side by side, people ignored Dave and stared at Kovacs. The structure was not perfect, but in terms of pure mass and shock factor, no one came close.
For women, he points to Iris Kyle. He believes at her best she had the greatest female physique of all time, comparing her impact to Ronnie Coleman. In clothes she did not look huge, but onstage she was unreal.
PCT, TRT and age Another viewer asks if PCT is needed after 60 or if you should just go straight to TRT. Dave says it depends on your goals.
If you still compete and run full cycles, he wants you to do a full cleanout: • Two weeks HCG • Two weeks Clomid • Then four weeks completely off
That break lets androgen receptors upregulate so you respond better to the next cycle or even standard TRT. If you are done competing and only want to feel good on lifelong replacement, you can go directly to TRT and stay there.
Statins, heart scans, and dementia risk On statins, Dave is firm. If your cardiac CT scan with contrast shows a very low score and clean arteries, he would not touch statins even with high LDL. Cholesterol is needed to repair myelin sheaths for nerve function, so drugs that crush cholesterol worry him for brain health. He notes links between long-term statin use and early dementia.
He would only consider statins in a serious high-risk case: strong family history, high cholesterol, and proven plaque in the arteries.
News, RX content and why this episode is worth watching Near the end, they update viewers on RX Muscle shows. They talk about an emotional After Hours episode with Amin Ali before he reports to prison, clarify the toxicology report on the death of Haley McNabb, and plug Heavy Muscle Radio where they break down Andrew Jacked’s big win at the Romania Pro and what it could mean for the 2026 Olympia lineup.
If you care about bodybuilding health, gear, smart supplement use, and freaky mass legends like Greg Kovacs and Iris Kyle, this Ask Dave episode is a strong watch.








