Workingatit46
Well-known member
Member
- Joined
- Apr 1, 2008
- Messages
- 325
- Points
- 16
It is too big to copy and paste the article, so I will provide a link.
Trans-Resveratrol
Trans-Resveratrol
Last edited by a moderator:
Legal Notice – MuscleMecca Forums
MuscleMecca.com is an educational discussion platform. We do not sell, promote, or endorse any bodybuilding gear, supplements, research chemicals, or performance-enhancing substances.
All discussions are for educational and informational purposes only. Nothing posted on this forum should be considered medical or legal advice.
Do not attempt to sell, source, or promote illegal substances. Any such activity will result in an immediate and permanent ban and may be reported to the proper authorities.
By using this site, you agree to comply with all forum rules, disclaimers, and applicable laws in your jurisdiction.
Resveratrol has a problem though, and it concerns its bioavailability. When you consume resveratrol it is absorbed adequately into the blood stream but after that it is very quickly sulfated and glucuronidated by enzymes. What this means is that it is transformed into inactive derivatives meant for elimination from the body. To get an active quantity of resveratrol into the body you have to overcome this problem. This is done by simultaneously ingesting compounds (quercetin and piperine) that will use up these enzymes preferentially, leaving the resveratrol free to circulate in the body. A large dose must also be taken, as the enzyme blocking will only be partially effective.
does anyone have any experience with the stuff?
Stoked looks like a good product, I'd also combine it with some naringen, or just drink a glass of red wine and eat some grapes/grapefruit with it as well. Not sure if anybody has ever heard you aren't supposed to take medications with grape juice, but it's due to the inhibition of cytochrome P450 isoenzymes which causes too high a bioavailability for the drug.
I agree to the Terms of Service and Privacy Policy and acknowledge the following:
MuscleMecca.com does not sell, promote, or endorse any bodybuilding gear, supplements, research chemicals, or pharmaceutical products.
Advertisers are fully responsible for their content. Use this section at your own risk.
All discussions are for educational and informational purposes only and should not be interpreted as medical, legal, or purchasing advice.
Illegal activity is strictly prohibited and may result in permanent bans.