Tiger Fitness
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- Sep 12, 2021
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Mark Lobliner breaks down a new study on the ingredient 1,3-butanediol, and he does not hold back. He calls it one of the weakest, most biased studies he has ever seen published, and he explains why the supplement industry keeps pushing this ingredient despite major safety concerns.
He starts by explaining the problem. True ketone supplements like GoBHB support energy and performance. But 1,3-butanediol is a fake ketone precursor. It can turn into ketones in the liver, but it also drains ATP and shows signs of liver toxicity. Some companies even market it as an alcohol replacement. That alone raises red flags.
The real issue is the study behind it. Mark points out that the company selling the ingredient funded the study, conducted the study, and even used its own employees as test subjects. It was not blinded. There was no placebo. There was no comparison group. Participants took the product at home with no supervision, and they entered their own data, including several readings that were clearly wrong and later “fixed” by the researchers.
He shows how unsafe the product looked even in this friendly environment. Forty percent of employees reported dizziness. Thirty percent had severe stomach problems. With only 26 people in the study, the sample size was too small to draw any real conclusions.
Mark explains how real studies should work. They need independent researchers, proper controls, a placebo group, validated measurements, and enough participants to produce reliable results. He compares this to studies he has funded, which use double-blind designs, reputable researchers, and solid methodology.
He stresses that this flawed study is product promotion disguised as science. No bloodwork was taken. No long-term safety markers were measured. The entire observation window was only five hours. For a supplement some companies want people to take daily, that is meaningless.
Mark ends by pushing back on the misleading ketone hype. He defends GoBHB as a legitimate technology with ongoing research and real-world use. He shares stories from athletes who feel sharper and more energized without relying on caffeine, and he explains why he believes true ketones have powerful long-term benefits.
While the video is packed with humor and frustration, the message is clear. Bad science hurts consumers. Marketing shortcuts put people at risk. And before trusting a supplement, you need real data from real studies, not a company testing its own product on its own employees.
This is a must-watch video for anyone who uses supplements, follows fitness science, or cares about the truth behind the products they buy.
He starts by explaining the problem. True ketone supplements like GoBHB support energy and performance. But 1,3-butanediol is a fake ketone precursor. It can turn into ketones in the liver, but it also drains ATP and shows signs of liver toxicity. Some companies even market it as an alcohol replacement. That alone raises red flags.
The real issue is the study behind it. Mark points out that the company selling the ingredient funded the study, conducted the study, and even used its own employees as test subjects. It was not blinded. There was no placebo. There was no comparison group. Participants took the product at home with no supervision, and they entered their own data, including several readings that were clearly wrong and later “fixed” by the researchers.
He shows how unsafe the product looked even in this friendly environment. Forty percent of employees reported dizziness. Thirty percent had severe stomach problems. With only 26 people in the study, the sample size was too small to draw any real conclusions.
Mark explains how real studies should work. They need independent researchers, proper controls, a placebo group, validated measurements, and enough participants to produce reliable results. He compares this to studies he has funded, which use double-blind designs, reputable researchers, and solid methodology.
He stresses that this flawed study is product promotion disguised as science. No bloodwork was taken. No long-term safety markers were measured. The entire observation window was only five hours. For a supplement some companies want people to take daily, that is meaningless.
Mark ends by pushing back on the misleading ketone hype. He defends GoBHB as a legitimate technology with ongoing research and real-world use. He shares stories from athletes who feel sharper and more energized without relying on caffeine, and he explains why he believes true ketones have powerful long-term benefits.
While the video is packed with humor and frustration, the message is clear. Bad science hurts consumers. Marketing shortcuts put people at risk. And before trusting a supplement, you need real data from real studies, not a company testing its own product on its own employees.
This is a must-watch video for anyone who uses supplements, follows fitness science, or cares about the truth behind the products they buy.








